Genetic finding offers hope for orphan disease
New research conducted at UNC Lineberger Comprehensive Cancer Center, offers hope for people with a rare disorder called Chuvash polycythemia.
View ArticleResearchers use genomics to identify a molecular-based treatment for a viral...
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule...
View ArticleResearchers identify promising biomarkers and new therapeutic targets for...
Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney...
View ArticleResearchers find success with new immune approach to fighting some cancers
A national research collaboration of senior researchers, including a researcher from Moffitt Cancer Center, has found that 20 to 25 percent of "heavily pre-treated" patients with a variety of cancers...
View ArticleAbility to chart the molecular progress of diabetes brings personalized...
Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of...
View ArticleScientists identify natural compounds that enhance humans' perception of...
(Medical Xpress)—University of Florida taste scientist Linda Bartoshuk and her colleagues want to play a trick on you—but it's for your own good.
View ArticleResearchers identify possible drug target in breast cancer metastasis
The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers,...
View ArticleHundreds of alterations and potential drug targets to starve cancer tumors...
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia...
View ArticleTeam finds melatonin delays ALS symptom onset and death in mice
Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new...
View ArticleFusion and cell death in the development of skeletal muscle
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its...
View ArticleNew findings regarding DNA damage checkpoint mechanism in oxidative stress
In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species"—cell-damaging molecules that are byproducts of cellular metabolism—is...
View ArticleAmericans' vitamin D levels are highest in August, lowest in February, study...
UC Irvine and Mayo Clinic researchers have found that vitamin D levels in the U.S. population peak in August and bottom out in February. The essential vitamin – necessary for healthy bones – is...
View ArticleResearchers identify mechanism involved in causing cataracts in mice
Cataract is one of the most common eye diseases, becoming more prevalent as people age. Over half of adults in the United States develop cataracts before age 80 and more than six million have undergone...
View ArticleIntestinal protein may have role in ADHD, other neurological disorders
A biochemical pathway long associated with diarrhea and intestinal function may provide a new therapeutic target for treating ADHD (Attention Deficit Hyperactivity Disorder) other neuropsychiatric...
View ArticleScientists discover switch that turns white fat brown
Scientists have discovered a biological switch that gives energy-storing white fat the characteristics of energy-burning brown fat. The findings could lead to new strategies for treating obesity.
View ArticleCould hypertension drugs help people with Alzheimer's?
Within the next 20 years it is expected the number of people with Alzheimer's disease (AD) will double from its current figure of half a million to one million. A new study has looked at whether...
View ArticleWorms reveal secrets of wound-healing response
The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's...
View ArticleModified bone drug kills malaria parasite in mice
A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses...
View ArticleScientists pinpoint gene variations linked to higher risk of bipolar disorder
(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified small variations in a number of genes that are closely linked to an increased risk of...
View ArticleScientists find regulator linking exercise to bigger, stronger muscles
Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that...
View ArticleScientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with...
View ArticleResearchers define how a gene mutated in Parkinson's disease may normally...
(Medical Xpress)—Cell biologists studying Parkinson's disease are training their sights on mitochondria, the energy source of the cell, whose activity in neurons appears to go awry in this devastating...
View ArticleAntibiotics: A new understanding of sulfonamide nervous system side effects
Since the discovery of Prontosil in 1932, sulfonamide antibiotics have been used to combat a wide spectrum of bacterial infections, from acne to chlamydia and pneumonia. However, their side effects can...
View ArticleNeurochemical traffic signals may open new avenues for the treatment of...
Researchers at Boston University School of Medicine (BUSM) have uncovered important clues about a biochemical pathway in the brain that may one day expand treatment options for schizophrenia. The...
View ArticleMemory-boosting chemical identified in mice
Memory improved in mice injected with a small, drug-like molecule discovered by UCSF San Francisco researchers studying how cells respond to biological stress.
View ArticleStudy shows how the Nanog protein promotes growth of head and neck cancer
A study led by researchers at The Ohio State University Comprehensive Cancer Center-– Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) has identified a...
View ArticleDeadliest cancers may respond to new drug treatment strategy
UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called "myc," paving the way for patients with myc-driven cancers to enroll in clinical trials for...
View ArticlePossible new mechanism for aspirin's role in cancer prevention
Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it...
View ArticleStudy reveals new way lungs respond in asthma attacks
Scientists have discovered a new way in which the lungs operate during asthma that could lead to new treatments for the disease.
View ArticleAlcohol shown to act in same way as rapid antidepressants
Can having a few drinks help people with clinical depression feel better?
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